化水对公共健康的影响:来自快速系统审查的现有证据
Fatemeh V Zohoori1, Elizabeth A Kumah2, Jelena Kronic1
1School of Health and Life Sciences, Teesside University, Middlesbrough, United Kingdom.
Advances in nutrition (Bethesda, Md.)
|October 24, 2025
概括
在建议水平下,社区水的化是安全的. 一项审查发现1.0mg/L以下没有令人信服的危害,但对于更高化物度需要更多的研究.
科学领域:
- 环境健康 环境健康
- 公共卫生政策 公共卫生政策
- 毒理学 毒理学 毒理学
背景情况:
- 80多年来,社区水的化一直是公共卫生实践.
- 关于危害的断言需要持续审查证据,以告知政策.
- 饮用水化物暴露的人类非牙健康结果需要检查.
研究的目的:
- 系统地审查与社区水化所产生的化物暴露相关的人类非牙科健康结果.
- 评估有关潜在不良健康影响的证据基础.
- 为了告知公共卫生政策的水化.
主要方法:
- 进行了快速系统的文献审查.
- 搜索包括多个数据库 (Medline,PubMed,Scopus等). 和灰色的文学.
- 混合方法评估工具 (MMAT) 用于质量评估;元分析是不可行的.
主要成果:
- 包括58项研究,大多数被认为具有可接受的质量,但往往对混因素的控制不足.
- 观察到一些关于儿童的神经和甲状腺不良影响的证据,以及成人血压,甲状腺和骨影响的证据,通常在化物度>1.5 mg/L时.
- 在儿童或成年人中,度<1.0 mg/L时没有发现任何不良影响.
结论:
- 没有确定任何令人信服的证据表明社区水化0.7-1.0毫克/升的危害.
- 对于高化物度 (>1.5 mg/L) 的潜在不良影响仍然存在不确定性.
- 方法上的局限性需要更严格的未来研究来确定因果关系.
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