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Updated: Jan 14, 2026

Measurement of Natural Killer Cell-Mediated Cytotoxicity and Migration in the Context of Hepatic Tumor Cells
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BDA-366通过通过NF-κB通路诱导线粒体损伤来抑制额外节点自然杀手/T细胞淋巴瘤

Jiali Wu1, Ping Zhang1, Chunju Ji2

  • 1Department of Hematology, Peking University Shenzhen Hospital, Shenzhen, China.

Biochemical pharmacology
|October 24, 2025
PubMed
概括

一种新的BCL-2 BH4域抑制剂,BDA-366,显示出强大的抗瘤作用,可以对抗额外结节自然杀手/T细胞淋巴瘤 (ENKTL). 这种药物有效诱导亡并抑制瘤生长,为耐化疗ENKTL患者提供了有前途的新疗法.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.这就是BDA-3666.这是一个 ENKTLTL ENKTL.在 NF-κBB 中.

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