心律不整以及睡眠障碍
Catherine M Heinzinger1, Reena Mehra2
1Sleep Disorders Center, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue/S73, Cleveland, OH 44195, USA. Electronic address: https://twitter.com/DrHeinZzzinger.
睡眠呼吸障碍与心律不整如心房动有很强的联系. 治疗睡眠呼吸障碍可能会减少心房的复发.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 内部医学 内部医学
背景情况:
- 睡眠呼吸障碍 (SDB),定期四肢运动,失眠和睡眠缩短与心律不整有关.
- 这种联系在SDB和心房动 (AF) 之间是最一致和最显著的.
研究的目的:
- 审查睡眠障碍与心律不整之间的关联.
- 探索潜在的机制和治疗影响.
主要方法:
- 社区和临床队列研究的审查.
- 对动物实验模型的发现进行分析.
- 评估非随机干预研究.
主要成果:
- 最强有力的证据将SDB和AF联系起来.
- 机制包括自主神经系统波动,胸内压力变化和间歇性缺氧.
- SDB治疗可能会减少AF复发后的消去或心脏转变.
结论:
- SDB是心律不整的重要危险因素,特别是AF.
- 了解这些机制可以指导治疗策略.
- 对于SDB的干预在管理AF方面表现有希望.
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