计算机断层扫描和磁共振成像对比介质的指导方针和争议
Madeleine Sertic1, Daniel I Glazer2
1Department of Radiology, Division of Abdominal Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Radiologic clinics of North America
|October 24, 2025
概括
对比介质增强医学成像,如CT和MRI,但可能导致不良事件. 指南有助于选择患者并减轻诸如过敏反应和损伤等风险.
科学领域:
- 放射学和医学成像学 医学成像学
- 诊断剂的药理学 诊断剂的药理学
背景情况:
- 对比介质在计算机断层扫描 (CT) 和磁共振成像 (MRI) 中被广泛使用,以提高诊断准确度.
- 尽管总体安全,但潜在的不良事件需要仔细考虑.
- 关键的安全问题包括过敏类反应,因剂引起的对比引起的急性损伤 (CI-AKI) 和因加多剂引起的性全身纤维化 (NSF).
研究的目的:
- 总结医学成像中使用的对比介质的安全性概况.
- 概述与对比介质管理相关的主要风险.
- 突出专业指南在降低风险方面的作用.
主要方法:
- 关于对比介质安全的当前文献的综述.
- 分析与含有和加多的对比剂相关的报道不良事件.
- 检查美国放射学学院 (ACR) 关于患者选择和风险管理的指导方针.
主要成果:
- 对比介质的使用与几种潜在的不良事件有关.
- 过敏类反应是不同类型对比的常见问题.
- 含的对比剂构成CI-AKI的风险,而加多剂与NSF有关.
结论:
- 虽然对比介质对于诊断成像至关重要,但它们的管理需要意识到潜在的风险.
- 遵守患者选择和风险减轻策略的既定准则至关重要.
- 积极管理可以最大限度地减少对比介质相关不良事件的发生率和严重程度.
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