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Updated: Jan 14, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
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戈尔吉相关的TRAF6作为蛋白转化酶FURIN调节剂,用于胰岛素受体前体加工

Minjun Liu1,2, Kun Zhou3, Yang Sheng1,2

  • 1State Key Laboratory of Pharmaceutical Biotechnology, Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, School of Medicine, Nanjing University, Nanjing, 210061, China.

Science China. Life sciences
|October 24, 2025
PubMed
概括

肥胖会通过降低胰岛素受体 (INSR) 来加剧胰岛素抵抗. 通过TRAF6 E3-酶的非激活,可以防止INSR的减少,改善葡萄糖的吸收和抑制糖的产生,提供代谢控制的洞察力.

关键词:
弗林 (Furin) 是一个古老的食物.在TRAF6中,胰岛素受体的胰岛素受体胰岛素敏感性 胰岛素敏感性自己的蛋白质加工加工.无处不在的化

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