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μOR-连接体:针对μ-阿片类受体连接体功能分类的基于目标感知视图的混合特征选择

Sadettin Y Ugurlu1,2

  • 1Novexus Ltd, 07058, Antalya, Turkey. s.yavuz.ugurlu@gmail.com.

Journal of computer-aided molecular design
|October 24, 2025
PubMed
概括

本研究引入了μOR-Ligand框架,通过整合连接体和标相互作用特征,改进了人类μ-阿片类受体 (μOR) 的agonist与antagonist分类. 这种新的方法提高了药物发现和安全性评估的准确性.

关键词:
在 μOR 和 μOR 之间.作为一个μOR激动剂.μOR 抗剂的使用.基于视图的组合特征选择选择.基于视图的混合功能选择.基于视图的多型车功能选择.

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