人类乳头瘤病毒感染的流行率,基因型分布和清除时间:一项回顾性研究
Nawfal R Hussein1, Halder J Abozait1, Nashwan Mr Ibrahim2
1Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, Kurdistan Region, Iraq.
Medicine
|October 25, 2025
概括
人类乳头瘤病毒 (HPV) 感染在伊拉克杜霍克测试的成年人中非常普遍,男性的发病率更高. 了解HPV基因型分布和清除对于公共卫生战略至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 病毒学 病毒学
背景情况:
- 人类乳头瘤病毒 (HPV) 是全球常见的性传播感染,与各种癌症有关.
- 关于伊拉克的HPV流行,基因型分布和清除的数据有限.
研究的目的:
- 为了确定HPV患病率,基因型分布和成年人感染清除时间,在伊拉克杜霍克市进行了测试.
- 为该地区的公共卫生战略和预防政策提供信息.
主要方法:
- 对802名成年人 (18岁以上) 进行HPV检测的回顾性横截面研究.
- 基于PCR的测试用于从宫,阴茎和尿道样本中识别36种HPV基因型.
- 统计分析包括流行率估计,基因型分布和卡普兰-梅尔清除时间分析.
主要成果:
- 总体HPV患病率为38.8%,男性 (53.7%) 比女性 (35%) 高.
- 在18.5%的患者中发现高风险HPV基因型,在31.5%的患者中发现低风险;53.7%的患者患有多重感染.
- 常见的基因型:HPV6,62,81,11 (低风险);HPV56,66,16 (高风险). 其他
- 平均清除时间:163天 (男性),243天 (女性).
结论:
- 在研究的杜霍克人口中,HPV感染非常普遍,具有显著的基因型多样性,男性的发病率更高.
- 调查结果强调了伊拉克需要HPV疫苗接种,扩大查和量身定制的公共卫生战略.
- 进一步以人口为基础的研究对于指导有效的预防政策至关重要.
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