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Updated: Jan 14, 2026

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灭菌级膜/预过器的表征和对mRNA-LNP过程开发的应用

Kevork Oliver Messerian1,2, Anton Zverev2, Jack F Kramarczyk2

  • 1Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, USA.

Biotechnology and bioengineering
|October 25, 2025
PubMed
概括

选择正确的灭菌级过器对于脂质纳米粒子 (LNP) 生产至关重要. 膜毛孔尺寸分布显著影响LNP过能力和污染,双层过器提供了增强的性能.

关键词:
脂质纳米粒子 (LNP) 是一种这是mRNA疫苗.入侵孔径测量 入侵孔径测量预先过的过方法无菌过的过方式.

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