全球对代谢功能障碍相关的稳态性肝病 (MASLD) 和代谢功能障碍相关的稳态性肝炎 (MASH) 的研究进行系统地映射
Melissa Lou Silva1, Renan Prado2
1Department of Radiology, Liver Imaging Group, University of California San Diego, San Diego, USA.
Digestive diseases and sciences
|October 25, 2025
概括
全球对代谢功能障碍相关的肥胖性肝病 (MASLD) 和肥胖性肝炎 (MASH) 的研究集中在少数国家和机构,在高度引用的论文中指出了作者身份的显著性别差异.
科学领域:
- 肝病学和胃肠病学 肝病学和胃肠学
- 公共卫生和流行病学
- 图书统计学和研究影响力
背景情况:
- 代谢功能障碍相关的脂肪性肝病 (MASLD) 是一种普遍存在的全球性肝病,代谢功能障碍相关的脂肪性肝炎 (MASH) 在一个显著的子集中发展.
- 虽然MASLD/MASH的人口水平差异是已知的,但科学文献中的不平等仍然未得到充分探索.
- 了解研究模式对于应对全球卫生挑战和促进公平的科学进步至关重要.
研究的目的:
- 系统地绘制全球MASLD/MASH研究成果并确定趋势.
- 分析地理分布,机构贡献和作者模式.
- 调查研究生产率和代表性的差异.
主要方法:
- 从1980年到2024年使用Web of Science核心集合对36,268篇出版物的图书统计分析.
- 通过Bibliometrix R包评估年度生产,国家和机构贡献.
- 对1000篇最多引用的文章进行差异分析,重点关注国家,第一作者性别和期刊代表性.
主要成果:
- 马斯德/马什研究迅速增长,出版物在2010-2020年之间达到顶峰.
- 美国主导着研究成果和引用;主要期刊包括肝病学,肝病学杂志和胃肠病学.
- 存在显著的性别差异,只有3%的顶级论文由女性第一作者撰写,这凸显了研究工作的集中.
结论:
- 在地理,期刊和作者方面,MASLD/MASH研究的集中度很高.
- 在该领域内,在作者的代表性方面存在明显的性别差异.
- 加强包容性和促进国际合作对于MASLD/MASH研究的未来进展至关重要.
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