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胰腺固体伪毛囊性瘤的治疗方法和结果:系统性审查
Arianna Pontrelli1, Giovanna Di Meo1, Francesco Paolo Prete1
1Department of Precision and Regenerative Medicine and Jonian Area (DiMePRe-J), Academic General Surgery Unit "V. Bonomo", University of Bari, Bari, Italy.
Clinical and experimental medicine
|October 25, 2025
概括
胰腺的固体伪皮质瘤 (SPN-P) 是罕见的. 手术干预是黄金标准的治疗方法,提供了有利的结果,尽管胰腺抽是常见的并发症,特别是在帕伦基马保护手术中.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 胰腺疾病 胰腺疾病
背景情况:
- 胰腺固体伪皮质瘤 (SPN-P) 是一种罕见的胰腺瘤,占外分泌瘤的0.9-2.7%和囊性胰腺瘤的5%.
- 关于SPN-P的临床,外科和瘤特征和结果的证据有限.
研究的目的:
- 系统地审查SPN-P的临床特征,手术管理以及短期和长期的手术和瘤结果.
主要方法:
- 从2004年1月到2024年8月,在四个数据库 (MEDLINE/PubMed,科学网,Scopus,Cochrane图书馆) 进行了系统审查.
- 分析了54项符合条件的研究,其中包括1888名SPN-P患者的数据.
主要成果:
- 大多数患者 (85.6%) 是女性,平均年龄为30.7岁.
- 在1882名患者中进行了手术,其中1869人接受了胰腺切除.
- 手术后的胰腺是最常见的并发症 (23%),特别是在护囊细胞保存手术后. 其他并发症包括伤口感染,腹腔内收集,胃排空延迟和胰腺功能不充分.
结论:
- 手术干预是SPN-P治疗的黄金标准,产生了有利的瘤结果和出色的预后.
- 需要进一步的研究来解决SPN-P手术管理的未解决方面,并优化治疗方案.
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