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较高的饮食炎症指数与非COPD成年人的肺功能下降有关:NHANES 2007-2012的横截面研究
Xuefeng Li1, Qiang Wang2, Youmei Wang3
1Department of Thoracic Oncology, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, China.
Nutrition research (New York, N.Y.)
|October 25, 2025
概括
通过更高的饮食炎症指数 (DII) 表示的促炎症饮食与非COPD成年人的肺功能 (FEV1和FVC) 降低有关. 这种关联在肥胖个体中较弱.
科学领域:
- 营养科学 营养科学
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 在非慢性阻塞性肺病 (非COPD) 患者群体中,饮食和肺功能之间的关系尚不清楚.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
研究的目的:
- 在非COPD人群中调查饮食炎症指数 (DII) 和肺功能测量 (FEV1,FVC) 之间的关联.
- 探索肥胖对这种关联的潜在影响修改.
主要方法:
- 分析了NHANES (2007-2012) 队列中的7990名参与者的数据.
- 从24小时的饮食回忆中计算DII得分,并将其分类为第三类.
- 多变量线性回归和受限立方线分析,调整混因子,对肥胖的子组分析.
主要成果:
- 每个单位的DII增加都与FEV1 (23.16毫升) 和FVC (34.95毫升) 的显著降低有关 (p < .001).
- 较高的DII三位数与最低三位数 (p < .001) 相比,显示出明显较低的FEV1和FVC.
- 在肥胖个体中,DII与肺功能之间的关联较弱,FEV1的显著相互作用 (P = .015).
结论:
- 具有较高DII的促炎性饮食与没有COPD的中年成人肺功能有负面关联.
- 肥胖可能会减轻促炎症饮食对肺功能的有害影响.
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