步行速度和事件抑郁:一个系统的审查和元分析
Maria Eduarda A Guimarães1, Marilia G da Silva2, Raissa Machado2
1Institute of Psychiatry of Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Journal of affective disorders
|October 25, 2025
概括
步行速度较慢与成年人患抑郁症的风险较高有关. 这一发现表明,步行速度可以作为抑郁风险的早期指标.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 未来研究表明,身体功能与心理健康之间存在联系.
- 步行速度是老年人身体表现的关键指标.
- 抑郁症是一个重要的公共卫生问题,特别是在老年人群中.
研究的目的:
- 系统地审查和元分析步行速度和事件抑郁之间的关联.
- 要确定步行速度较慢是否预测成年人患抑郁症的发展.
- 巩固前性队列研究的证据.
主要方法:
- 进行了符合PRISMA 2020标准的系统审查.
- 在PubMed,Embase,Web of Science和PsycINFO进行了搜索.
- 对10项队列研究的数据进行了几率比率 (OR) 和危险比率 (HR) 的元分析,使用纽卡斯尔-太华尺度评估偏差风险.
主要成果:
- 包括10项涉及超过10万名成年人的研究.
- 步行速度较慢与发生抑郁症的几率增加有关 (OR = 1.30,95% CI = 1.03-1.66).
- 通过危险比率 (HR = 1.17,95% CI = 1.08-1.28) 证实了这种关联,没有根据年龄,性别或随访持续时间显著的适度.
结论:
- 步行速度较慢是成年人发生抑郁症的重要预测因素.
- 步行速度可以作为一种非侵入性生物标志物,用于识别患有抑郁症风险的个体.
- 需要进一步的研究,将步行速度纳入抑郁症预测模型.
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