连接辅助运动网络和执行功能在发育大脑中的作用
Dong-Gyun Han1, Bumhee Park2,3,4,5,6, Seulgi Lee2,3
1Department of Psychiatry, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
概括
补充运动区域 (SMA) 与其他大脑区域的功能连接与青少年的执行功能 (EF) 有关. 这种对认知发展至关重要的联系在11-12岁左右出现.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 认知科学 认知科学
背景情况:
- 额叶的发育对于儿童和青少年期间的执行功能 (EF) 是至关重要的.
- 补充运动区域 (SMA) 在高阶EF中起着关键作用,如抑制,工作记忆和认知灵活性.
- SMA功能网络与EF发展之间的确切关系仍未得到充分探索.
研究的目的:
- 调查SMA功能连接 (FC) 中与年龄相关的差异.
- 确定SMA FC如何与儿童和青少年的执行功能发展有关.
- 确定与EF相关的SMA网络成熟的关键发展时期.
主要方法:
- 使用了静止状态功能磁共振成像 (fMRI) 数据.
- 评估威斯康星州卡片排序测试 (WCST) 的表现作为EF的衡量标准.
- 分析了来自112名年龄在6至17岁的参与者的数据.
主要成果:
- 在老年青少年中确定了300个SMA和大脑广泛区域之间的显著FC.
- 这些FC,包括连接到额头部,部,部,部,边缘和小脑区域,与WCST性能有负相关性.
- 与EF相关的关键的SMA功能连接性在年轻的参与者中不存在.
结论:
- 这些发现突显了SMA在执行功能发展和潜在的执行功能障碍中的重要作用.
- 11-12岁的年龄段似乎是EF相关的大脑功能改变的关键时期.
- 这项研究为SMA功能成熟和EF发展轨迹的个体差异提供了新的见解.
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