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双J支架与非支架在儿科脏移植:一个回顾性单中心比较研究
Roberto Vagni1, Pedro Mercado1, Alejandro Calvillo-Ramirez2
1Department of Pediatric Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
International urology and nephrology
|October 27, 2025
概括
在儿科移植 (KT) 中,双J支架 (DJS) 并没有显著减少泌尿系统并发症. 在DJS和非DJS组之间,移植生存率和肌素清除率相似,这表明DJS可能只对特定的高风险儿童有益.
科学领域:
- 儿科脏病学 儿科脏病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 移植手术 移植手术
背景情况:
- 移植 (KT) 是对儿科末期病的主要治疗方法.
- 双J支架 (DJS) 是一项备受争议的技术,用于预防KT后的泌尿病并发症.
- 关于DJS在儿科KT的疗效的证据有限.
研究的目的:
- 评估DJS对儿科KT泌尿和血管并发症的影响.
- 为了比较患有DJS和没有DJS的儿科KT患者之间的移植损失和肌素清除.
- 评估DJS在改善儿科脏移植接受者的结果方面的整体有效性.
主要方法:
- 从2010年1月到2021年12月的儿科KT病例的回顾性审查.
- 在DJS和非DJS组之间比较泌尿病,血管并发症,移植损失和肌素清除.
- 分析包括患有先前存在的尿路病变,尿道疾病或尿道-尿道瘤的患者.
主要成果:
- 总共分析了156名儿科KT (84名DJS,72名非DJS).
- 尿道并发症的发生率在DJS组 (20.8%) 与非DJS组 (9.5%) 中较高,但在统计学上不显著 (p=0.07).
- 血管并发症,移植损失和1年的肌素清除在两组之间是相似的.
结论:
- 儿童KT中的DJS似乎没有减少泌尿道并发症.
- 在DJS和非DJS儿科KT患者中,移植存活率和一年后肌素清除值在DJS和非DJS儿科KT患者中相似.
- DJS可能为特定的高风险儿科KT候选人提供福利.
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