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Updated: Jun 16, 2026

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使用CRISPR干扰在Mycobacterium的多重,基于目标的表型查平台

Donavan Marcus Neo1,2,3, Ishay Ben-Zion1, Josephine Bagnall1

  • 1Center for Integrated Solutions for Infectious Diseases, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.

ACS infectious diseases
|October 27, 2025
PubMed
概括

新的PROSPECT (主要查菌株以优先考虑扩展化学和标) 策略使用CRISPR干扰来寻找难以治疗的Mycobacterium疹感染的新药,识别向InhA的化合物.

关键词:
这就是CRISPR干扰的原因.这种细菌是Mycobacterium abscessus.抗生素的发现抗生素的发现化学遗传相互作用复合选 复合选 复合选 复合选 复合选高通量多重选选的多重选固有耐药性对异化的内在耐药性

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