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磁共振导向放射治疗 (MRgRT) 前列腺运动和边缘

Sammi Peng¹, Tegan Courtot², Jessica Lye²

¹Department of Medical Imaging and Radiation Sciences, School of Primary and Allied Health Care, Monash University, Melbourne, Australia.

Journal of medical radiation sciences

|October 27, 2025

概括

磁共振导向辐射疗法 (MRgRT) 允许在前列腺癌 (PCa) 治疗中减少计划目标体积 (PTV) 边缘. 然而,较长的治疗时间可能会增加前列腺运动,需要进一步研究最佳边缘策略.

科学领域:

辐射瘤学辐射瘤学
医疗成像医学成像
前列腺癌治疗方法前列腺癌治疗方法

背景情况:

规划目标体积 (PTV) 边缘对于准确的辐射剂量传递至关重要.
磁共振导向辐射疗法 (MRgRT) 为潜在的边际减少提供了改进的成像.
对于前列腺癌 (PCa) 的MRgRT中最佳的PTV边际需要进一步调查.

研究的目的:

为了评估在MRgRT期间的前列腺内断片运动.
为了确定接受MRgRT的PCa患者适当的PTV边际.
评估适应性放射治疗对PTV边缘的影响.

主要方法:

对18名PCa患者的回顾性分析,这些患者接受了1.5T MR-Linac治疗.
线下注册初始和验证MRI扫描以测量前列腺位移 (AP,LR,SI).
使用范赫克公式计算随机和系统错误和PTV边际.

主要成果:

平均转移位移:1.2±0.9毫米 (AP),0.6±0.5毫米 (LR),1.1±0.8毫米 (SI). 平均转移位移:1.2±0.9毫米 (AP),0.6±0.5毫米 (LR),1.1±0.8毫米 (SI). 平均转移位移:1.2±0.9毫米 (AP),0.6±0.5毫米 (LR),1.1±0.8毫米 (SI).
计算的PTV边缘:3.2毫米 (AP),1.7毫米 (LR),3.2毫米 (SI).
观察到前列腺运动增加的趋势与更长的治疗持续时间.

结论:

在PCa治疗中,MRgRT显示了减少PTV利的潜力.
沙发上的时间增加可能与前列腺运动增加有关.
建议对更大的队列和实时监测进行进一步的研究,以优化保证金策略.

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