在中国仓鼠卵巢细胞中对抗体糖化调节:实验和计算分析提供了机械洞察力

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Updated: Jan 14, 2026

Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells
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Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells

Published on: June 2, 2022

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Ranya Pranomphon1,2, Sofia Gialamoidou3, Montarop Yamabhai2

  • 1Department of Nanoscale Science and Engineering, College of Nanotechnology, Science, and Engineering and The RNA Institute, University at Albany, State University of New York, Albany, New York, USA.

Biotechnology journal
|October 27, 2025
PubMed
概括

补充和银河糖的细胞培养基可以协同增强抗体银河化. 数学建模显示,尿素三酸盐度限制了甘氨酸合成,影响了CHO-K1细胞中的抗体甘氨基化概况.

关键词:
在CHO细胞中.生物类似药的生物类似药.培养方式调节葡萄糖酶化是什么? 葡萄糖酶化是什么?数学建模的数学建模一个单克隆抗体.

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