由Plectosphaerella cucumerina引起的与腹膜透析相关的罕见腹膜炎:一个病例报告
Guofeng Mao1, Meichun Liang1, Qiaoli Wu1
1Department of Clinical Laboratory Center, Shaoxing People's Hospital, Shaoxing, 312000, PR China.
The new microbiologica
|October 27, 2025
概括
本病例报告详细介绍了Plectosphaerella cucumerina (P. cucumerina) 在接受腹膜透析的患者中引起腹膜炎的首例. 用可纳进行的抗真菌治疗对于这种罕见的真菌感染是有效的.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 斑菌 (Plectosphaerulla cucumerina) 是一种罕见的真菌病原体,主要影响植物.
- 人类感染P. cucumerina是非常罕见的.
- 腹膜透析 (PD) 相关的腹膜炎是功能衰竭患者的严重并发症.
研究的目的:
- 报告第一个由P. cucumerina引起的PD相关腹膜炎病例.
- 突出这一罕见的真菌感染的诊断和治疗挑战.
- 为了评估抗真菌治疗P. cucumerina外周炎的疗效.
主要方法:
- 诊断包括真菌培养,MALDI-TOF MS和基因测序.
- 监测了临床表现和实验室标记.
- 开始使用可纳治疗.
主要成果:
- 一名79岁的女性PD患者被诊断出患有P. cucumerina腹膜炎.
- 患者在弗卢科纳治疗三天内显著改善了临床情况.
- 在治疗两周后,炎症标志物正常化,表明治疗成功.
结论:
- P. cucumerina可以在PD患者中引起腹膜炎,尽管很少见.
- 培养和分子技术对于诊断P. cucumerina感染至关重要.
- 单独使用可纳治疗可以有效治疗P. cucumerina外周炎,强调早期诊断和向治疗.
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