关于腹腔内角膜炎的管理的审查
Pedro Puerta-Alcalde1,2,3, Jesús Guinea4,5,6,7, Emilio Maseda8,9
1Hospital Germans Trias i Pujol, Badalona, Spain.
概括
腹腔内角膜炎显著增加了ICU患者的死亡率和住院时间. 优化的多学科方法对于改善这些复杂感染的结果至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
背景情况:
- 腹腔内角膜炎,包括Candida腹膜炎和,占ICU诊断的腹腔内感染的10-30%.
- 与长时间住院,增加发病率和更高的死亡率有关.
- 尽管侵袭性 кандидоз治疗取得了进展,但腹腔内 кандидоз的最佳管理策略仍未得到充分定义.
研究的目的:
- 审查管理腹腔内角膜炎的关键挑战.
- 针对微生物学诊断,抗真菌剂量,腹腔内液透以及脂质体安二B的作用.
- 提供关于抗真菌耐药性,药理动力学/药理动力学和日常临床实践的见解.
主要方法:
- 文献综述侧重于微生物学诊断,抗真菌药物动力学/药物动力学和临床管理.
- 对有关抗真菌耐药性出现的当前数据的分析.
- 在重症监护病房设置中评估治疗策略.
主要成果:
- 微生物学诊断和抗真菌耐药性的风险是关键考虑因素.
- 抗真菌药物的药理动力学和药理动力学特性会影响治疗的疗效.
- 临床管理需要仔细考虑药物选择,剂量和来源控制.
结论:
- 优化的多学科方法对于改善患者的治疗结果至关重要.
- 快速诊断,量身定制的抗真菌疗法和有效的源控制至关重要.
- 解决诊断和治疗的不确定性可以提高腹腔内候群的预后.
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