非典型的轨道质量作为骨髓质疏松症候群复发的前体:一个病例报告
Nicholas Demas1, Janice Hernandez2, Peter Timoney2
1University of Kentucky College of Medicine, Lexington, KY, USA.
American journal of ophthalmology case reports
|October 27, 2025
概括
本案例研究详细介绍了一种罕见的急性髓性白血病 (AML) 病例,该病例呈现为患有骨髓发育综合征 (MDS) 病史的患者的隔离轨道质量. 早期诊断对于改善高风险AML患者的治疗结果至关重要.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 眼科医生 眼科 眼科
背景情况:
- 骨髓质疏松症候群 (MDS) 可以发展为急性骨髓性白血病 (AML).
- 颗粒细胞肉瘤是一种罕见的AML外骨髓性表现,有时在轨道上呈现,没有系统性疾病.
- 轨道质量可能是AML复发的不寻常的初始迹象.
研究的目的:
- 描述一个异常的孤立轨道质量的案例,作为AML复发的呈现标志.
- 强调在高风险患者中考虑AML的重要性,这些患者有不明原因的轨道症状.
- 为了突出外骨髓性AML呈现所带来的诊断挑战.
主要方法:
- 一个42岁的男性患有缓解的MDS病例报告.
- 临床表现:单侧眼睛疼痛,胀,视力模糊,双眼视,头.
- 诊断工作包括成像,多次活检和骨髓活检.
主要成果:
- 图像检查显示,有一个单边的内眼外质量.
- 最初的活检结果对恶性瘤呈阴性.
- 骨髓活检证实了AML的MDS复发.
结论:
- AML可以异常表现为一个孤立的轨道质量,即使在缓解.
- 临床怀疑和相关性至关重要,特别是当病理学研究是负面的.
- 及时诊断AML复发对于患者的管理和结果至关重要.
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