炎症性肠病患者对生物制剂的知识,态度和决策冲突:一个横截面研究
Qianqian Li1, Chenmei Xia1, Chunxiao Chen2
1Department of Gastroenterology, The First People's Hospital of Wenling (Taizhou University Affiliated Wenling Hospital), School of Medicine, Taizhou University, Taizhou, China.
Frontiers in medicine
|October 27, 2025
概括
中国的炎症性肠病 (IBD) 患者对生物治疗的知识和态度较低,如果他们年龄较大,有性结肠炎或有决策冲突. 教育干预措施可以改善患者对生物制剂的理解和接受.
科学领域:
- 胃肠病学 胃肠病学
- 患者健康素养 患者健康素养
- 生物疗法 生物疗法
背景情况:
- 生物疗法在治疗炎症性肠病 (IBD) 方面取得了重大进展.
- 了解患者的观点,包括知识,态度和决策冲突,对于有效的治疗策略至关重要.
- 在中国,有关IBD患者对生物制剂的理解和担忧的具体数据有限.
研究的目的:
- 评估中国IBD患者与生物治疗有关的知识,态度和决策冲突.
- 识别与不同水平的知识和对生物学的态度相关的因素.
- 为考虑生物治疗的IBD患者制定有针对性的教育干预措施提供信息.
主要方法:
- 在2023年7月至2024年1月期间,在中国对405名IBD患者进行了一项横截面研究.
- 数据是通过自主管理的调查问卷收集的,这些调查问卷评估了人口统计,知识,态度和决策冲突,使用决策冲突量表.
- 统计分析包括斯皮尔曼相关性和多变量分析以确定关联.
主要成果:
- 平均知识分数是6.03/11,平均态度分数是24.36/40. 14.8%的患者经历了重大决策冲突.
- 较低的知识和态度得分与年龄较大 (≥50岁),性结肠炎诊断,没有先前的生物使用以及重大决策冲突有关.
- 在知识和态度得分之间发现了正相关性 (r=0.554,p<0.001).
结论:
- 老年IBD患者,性结肠炎患者,没有先前的生物暴露,以及重大决策冲突表明对生物学的知识和态度较差.
- 决策冲突似乎是影响知识和态度的关键因素.
- 建议有针对性的教育干预措施来缓解决策冲突,并提高患者对IBD生物疗法的接受度.
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