在性结肠炎中肠道屏障的研究趋势:一本书法分析分析
1The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, China.
Frontiers in medicine
|October 27, 2025
概括
恢复肠道屏障完整性是性结肠炎 (UC) 治疗的关键. 研究表明,人们越来越关注传统中医药,向性分娩和UC治疗的临床翻译.
科学领域:
- 胃肠道学和免疫学
- 生物医学研究生物医学研究
- 图书统计学 图书统计学
背景情况:
- 性结肠炎 (UC) 与肠道屏障功能障碍有关.
- 恢复肠道屏障的完整性是UC的潜在治疗策略.
- 目前,该领域缺乏系统的调查.
研究的目的:
- 进行关于性结肠炎中肠道屏障功能障碍研究的文献分析.
- 确定关键的研究趋势,有影响力的出版物和合作模式.
- 在这个领域绘制科学成果的地图.
主要方法:
- 从Web of Science核心集合和Scopus中对1554篇文章进行了图书统计分析.
- 使用CiteSpace和VOSviewer进行数据分析和可视化.
- 确定了主要主题,国家,机构,作者,关键词和期刊.
主要成果:
- 自2020年以来,出版物的数量大幅增加,其中中国是主要贡献者.
- 中国和美国形成了一个核心的国际合作网络.
- 关键的研究主题包括传统中医,紧结修复,NF-κB/氧化应激通路,向性输送和临床翻译.
- 表皮屏障和有机体模型是新兴的研究重点.
- "炎症性肠病"是该领域的一个关键期刊.
结论:
- 肠道屏障是UC的关键治疗点,推动了多学科研究.
- 未来的研究应该将机制学研究与临床应用联系起来,以获得更好的结果.
- 公平的国际合作对于推进有针对性的干预策略至关重要.
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