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从花朵到功能:从Rhododendron arboreum提取物合成的氧化铁纳米颗粒的结构和生物医学探索

Iram Saba¹, Vivek K Dhiman², Susmitha Kalaichelvan²

¹Amity Institute of Biotechnology, Department of Biotechnology, Amity University Haryana, Gurugram (Manesar), Haryana - India.

Journal of Taibah University Medical Sciences

|October 27, 2025

概括

绿色合成氧化铁纳米颗粒 (α-Fe2O3 NPs) 使用Rhododendron arboreum提取物显示出强大的抗菌,抗炎和抗癌特性. 这些环保的纳米粒子提供了有前途的生物医学应用.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
绿色化学绿色化学

背景情况:

氧化铁纳米粒子 (α-Fe2O3 NPs) 在各种生物医学应用中至关重要.
开发可持续和环保的合成方法是纳米技术的一个重大挑战.

研究的目的:

为α-Fe2O3NP开发一种绿色合成方法,使用Rhododendron arboreum花提取物.
为了评估合成的α-Fe2O3NP对于潜在的生物医学应用.

主要方法:

绿色合成α-Fe2O3NP使用Rhododendron arboreum花提取物.
使用X射线衍射 (XRD),扫描电子显微镜 (SEM),能量分散式X射线光谱 (EDS),UV-Vis光谱和里埃变换红外光谱 (FTIR) 的表征.
对抗MCF-7乳腺癌细胞系的抗菌活性,抗炎性潜力和细胞毒性的评估.

主要成果:

合成的α-Fe2O3NP的水力动力直径为274.7nm,泽塔电位为-18.6mV.
通过XRD确认了晶体α-Fe2O3,平均晶体大小为32.03nm.
已证明具有强大的抗菌活性,显著的抗炎作用,以及对乳腺癌细胞有前途的细胞毒性 (IC50 = 22μg/mL).

结论:

使用Rhododendron arboreum花提取物成功合成了α-Fe2O3NP的绿色合成.
合成的NP显示出抗菌,抗炎和抗癌生物医学应用的巨大潜力.
这项研究突出了生产功能纳米材料的环保方法.

关键词:

抗菌剂抗菌剂抗菌剂这是一种抗癌药物.绿色合成是一种绿色合成.罗多树的树木体 (arboreum)α-Fe2O3纳米粒子是什么

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