肠道失调引起的炎症的生物标志物量化:一篇评论
Leqi Lin1, Jacob George2, Guozhen Liu1
1Integrated Devices and Intelligent Diagnosis (ID2) Laboratory, CUHKSZ-Boyalife Regenerative Medicine Engineering Joint Laboratory, School of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, People's Republic of China.
Journal of inflammation research
|October 27, 2025
概括
肠道失生症会引起炎症,增加疾病风险. 本综述探讨了肠道炎症机制和量化策略,以更好地了解疾病和治疗.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 生物医学工程 生物医学工程
背景情况:
- 肠道失调,肠道微生物群的不平衡,与各种健康问题有关.
- 肠道炎症增加了肠道的透性,并激活了免疫反应,导致炎症性,自身免疫性和代谢性疾病.
- 精确量化肠道衍生炎症对于了解疾病发展和创建有效的治疗方法至关重要.
研究的目的:
- 审查肠道炎症背后的机制.
- 为了识别肠道失生症介导炎症的标志物.
- 讨论当前和新兴的肠道失生症衍生的炎症量化策略.
主要方法:
- 对肠道失生症介导炎症的机制,标记物和量化技术的文献综述.
- 分析一次性/可穿戴生物传感器,生物医学成像,测序和基于人工智能的方法.
- 讨论该领域的挑战和未来方向.
主要成果:
- 肠道失生症通过增加肠道透性和免疫激活引发炎症.
- 各种标志物表明肠道失生症介导的炎症.
- 有多种量化策略可用,包括生物传感,成像,测序和人工智能.
结论:
- 精确量化肠道失生症介导的炎症对于疾病研究和治疗开发至关重要.
- 生物传感,成像,测序和人工智能的进步为准确的测量提供了有希望的途径.
- 应对当前的挑战将为改进的诊断和治疗方法铺平道路.
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