使用内镜超声波引导的剪切波弹性学对上部胃肠道亚皮质病变的定量评估
Takahiro Marukawa1, Kazuhiro Furukawa1, Ryoji Miyahara2
1Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya journal of medical science
|October 27, 2025
概括
新开发的内镜超声波引导的剪切波弹性学准确量化了上部胃肠道亚皮质病变中的组织度,有助于差异诊断.
科学领域:
- 胃肠病学 胃肠病学
- 医疗成像医学成像
- 生物物理学的生物物理.
背景情况:
- 剪波弹性图 (SWE) 量化了组织刚度,但最近已经适应了内镜超声波 (EUS).
- 对上部胃肠道亚皮质病变的准确表征对于诊断和管理至关重要.
研究的目的:
- 评估一种新的EUS指导的SWE技术用于诊断上部胃肠道亚皮质病变的实用性.
- 评估EUS引导的SWE在区分病变类型中的可行性和诊断性能.
主要方法:
- 在EUS指导的SWE中,对23名患有上部肠道上皮层病变的患者进行了SWE.
- 剪波速度 (Vs) 测量了组织度;中位数Vs (Vs-med) 使用五个最高可靠性指数 (VsN-med) 值进行计算.
- 组织病理学证实了诊断:12个胃肠道 stromal 瘤 (GISTs),7个leiomyomas,4个 schwannomas.
主要成果:
- EUS引导的SWE是可行的和安全的,没有任何并发症.
- 病变类型之间Vs-med值有显著差异:GISTs (2.46 m/s) 和 schwannomas (2.85 m/s) 比leiomyomas (1.73 m/s) 更为硬.
- 在VSN-med值中,病变类型之间没有显著差异 (GISTs: 40.5%,leiomyomas: 39%, schwannomas: 35.5%).
结论:
- 以EUS为指导的SWE是一种可行的,非侵入性的方法,用于客观量化上部GI亚皮质损伤硬度.
- 这种技术显示出作为这些病变差异诊断的有价值工具的潜力.
- 定量度测量可以帮助区分良性和潜在恶性亚皮质病变.
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