中性粒细胞-淋巴细胞比率作为精神分裂症严重性的潜在生物标志物:一个横截面研究
Rashmi Meena1, Ragini Meena2, Jiwan S Meena3
1Pathology, Hamidia Hospital/Gandhi Medical College, Bhopal, IND.
Cureus
|October 27, 2025
概括
中性粒细胞-淋巴细胞比率 (NLR) 与精神分裂症的严重程度有关. 较高的NLR表明疾病的严重程度更高,特别是在未接受治疗的患者中,这表明它可以用于监测精神分裂症.
科学领域:
- 精神病学是一个精神病学.
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
背景情况:
- 精神分裂症是一种复杂的精神疾病,其中炎症起着关键作用.
- 中性粒细胞-淋巴细胞比率 (NLR) 是疾病严重程度的潜在生物标志物.
研究的目的:
- 评估NLR和精神分裂症严重程度之间的关系.
- 为了比较治疗和未治疗的精神分裂症患者的炎症标志物.
主要方法:
- 一项对100名精神分裂症患者 (ICD-10诊断) 的横截面研究.
- 使用简要精神病学评分表 (BPRS) 测量症状严重程度.
- 中性粒细胞-淋巴细胞比率 (NLR) 是从全血细胞计数计算出来的.
主要成果:
- 与接受治疗的患者 (4.57 ± 1.90) 相比,未接受治疗的患者显示显著更高的NLR (8.94 ± 5.08).
- NLR与BPRS得分有很强的相关性 (r = 0.736,p < 0.001).
结论:
- 升高的NLR与精神分裂症严重程度的增加有关.
- NLR可以作为一个具有成本效益的辅助工具来监测精神分裂症和个性化治疗.
关键词:
抗精神病治疗是一种抗精神病治疗.生物标志物生物标志物美国BPRS的得分.全血细胞计数的完整数目.这是一种炎症炎症炎症炎症.医疗伴随性疾病 医疗伴随性疾病中性粒细胞-淋巴细胞比率.精神分裂症是一种精神分裂症.症状严重程度 症状严重程度更多相关视频
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