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相关概念视频

Vaccinations01:51

Vaccinations

51.2K
Overview
51.2K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

928
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
928
Development of Immunocompetence01:22

Development of Immunocompetence

784
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
784
Immunological Memory01:23

Immunological Memory

15.0K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
15.0K
Cancer Vaccines01:30

Cancer Vaccines

946
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
946

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Updated: Jan 14, 2026

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
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Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites

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疟疾疫苗:目前的发展和免疫学见解

Akanksha Verma1, Ritesh Ranjha2,3, Kuldeep Singh2,3

  • 1Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.

New microbes and new infections
|October 27, 2025
PubMed
概括

疟疾仍然是一个全球性的健康威胁,尤其对幼儿来说. 由于抗药性寄生虫,新的抗疟疾药物和疫苗至关重要,但Plasmodium.

关键词:
免疫反应是免疫反应.免疫治疗是一种免疫疗法.疟疾:疟疾是一种疾病.原菌 (Plasmodium falciparum) 是一种有毒的病毒.疫苗 疫苗 疫苗 疫苗

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科学领域:

  • 热带医学是一种热带医学.
  • 寄生虫学的寄生虫学
  • 疫苗学 疫苗学 疫苗学

背景情况:

  • 疟疾影响全球2.63亿人,不成比例地影响到5岁以下的儿童.
  • 耐药的杆菌寄生虫威胁着疟疾控制和消除工作.
  • 开发有效的疟疾疫苗是具有挑战性的,因为寄生虫的复杂性和多个生命阶段.

研究的目的:

  • 审查目前批准的疟疾疫苗的前景.
  • 讨论针对不同等离子杆菌生命阶段的新型疫苗候选人.
  • 突出了解宿主免疫反应和理想疫苗要求的进展.

主要方法:

  • 关于疟疾疫苗和免疫生物学的文献综述.
  • 对疟疾疫苗开发当前挑战的分析.
  • 讨论未来的方向和新的方法.

主要成果:

  • 世界卫生组织仅批准了两种疟疾疫苗.
  • 在识别宿主免疫反应和潜在的疫苗点方面取得了重大进展.
  • 新兴的新型疫苗候选人对不同等离子体生命阶段显示出希望.

结论:

  • 持续开发抗疟疾药物和疫苗至关重要.
  • 未来的疟疾疫苗可能针对多个Plasmodium生命阶段,以提高有效性.
  • 了解宿主免疫力是设计有效和持久疟疾疫苗的关键.