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Updated: Jan 14, 2026

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综合性多组体分析在体内识别流感病毒宿主因素

Leah P Shriver1,2,3, Benjamin J Polacco4,5,6, Manon Eckhardt4,5,6

  • 1Department of Chemistry, Washington University in Saint Louis, Saint Louis, MO 63130, USA.

iScience
|October 27, 2025
PubMed
概括

流感病毒感染改变了宿主细胞的过程. 研究人员确定了氨酸:糖氨酸氨基转移酶 (GATM) 作为一个关键因素,并阻止它减少病毒病理和炎症.

关键词:
生物计算方法是一种生物计算方法.代谢学 代谢学 代谢学模型生物模型生物.蛋白质组学是指蛋白质组学.文字转录学 (Transcriptomics) 是一个学科.病毒学 病毒学

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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