患有扩散性血管内凝血的老年患者的死亡率趋势:回顾性CDCWONDER分析 (1999-2020年)
Piyush Ratan1, Kritika2, Umair Iqbal3
1Patna Medical College, Patna, India.
Archives of medical sciences. Atherosclerotic diseases
|October 27, 2025
概括
在老年人中,传播性血管内凝血 (DIC) 的死亡率最初下降,但最近已经上升. 仍然存在显著的种族和地区差异,突出了针对性干预措施解决这些不平等的必要性.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 传播性血管内凝血 (DIC) 是一种严重的疾病,在美国一般人口中死亡率趋势不断上升.
- 以前没有分析过DIC的老年人 (65岁以上) 死亡率趋势.
研究的目的:
- 分析在美国被诊断患有扩散性血管内凝血 (DIC) 的老年患者的死亡趋势.
- 确定老年人中与DIC相关的死亡率的人口和地理差异.
主要方法:
- 来自CDC WONDER数据库 (1999-2020) 的死亡证明数据的分析.
- 根据年龄调整的死亡率 (AAMR) 和年度百分比变化 (APC) 的计算.
- 根据年龄,性别,种族/族裔和地理区域对死亡率数据的分层.
主要成果:
- 在65岁以上的成年人中,DIC的整体年龄调整后死亡率在2015年之前从每10万人中从6.4降至4.0降低,然后略有增加.
- 死亡率趋势因性别,种族和地区而异,非洲裔美国人和美国南部地区的死亡负担最高.
- 大多数与DIC相关的死亡 (93.1%) 发生在医疗机构内.
结论:
- 尽管总体下降,但老年人中与DIC相关的死亡率最近呈现上升趋势.
- 在种族群体 (在非洲裔美国人中最高) 和地理区域 (在美国南部最高) 之间存在着持续的死亡负担差异.
- 针对性干预和加强监测对于解决这些差异和缓解死亡率上升至关重要.
相关概念视频
Venous Thrombosis III: Interprofessional Care
276
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
276
Venous Thrombosis IV: Nursing Management
192
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
192
Disorders of Hemostasis
2.0K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.0K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
227
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
227
Coagulation
9.6K
The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
9.6K
Coagulation
1.2K
Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
1.2K

