通过中部早期青春期的男性儿科患者的成像发现:一个病例报告
Raisa Mahmudah1, Radinda Amalia Nur Hayati1, Harry Galuh Nugraha1
1Department of Radiology, Faculty of Medicine Padjadjaran University, Dr. Hasan Sadikin Hospital Bandung, West Java, Indonesia.
Radiology case reports
|October 27, 2025
概括
中部早熟青春期 (CPP) 是性发育的早期开始. 一名患有CPP的5岁男孩被诊断出患有垂体小腺瘤,这突显了神经影像在诊断中的重要性.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 神经内分泌学神经内分泌学
- 放射学 放射学是一门学科.
背景情况:
- 早期青春期 (PP) 被定义为女孩在8岁和男孩在9岁之前二次性特征的早期发作.
- 中部早期青春期 (CPP) 源于下丘脑-垂体-腺 (HPG) 轴的过早激活.
- 虽然在女性中具有特异性,但在男性中CPP通常表明下丘脑-垂体病变.
研究的目的:
- 在一个年轻的男性中呈现一个中心早期青春期的病例.
- 为了说明CPP的诊断过程,包括临床评估和神经成像.
- 在本案中确定CPP的根本原因.
主要方法:
- 临床评估包括患者病史,体检和Tanner分期由儿科内分泌学家.
- 实验室评估以评估荷尔蒙状况和丸体积.
- 骨成熟度评估 (骨年龄估计).
- 诊断成像包括超声波和脑MRI,以检测内异常或垂体病理.
主要成果:
- 一个5岁的男孩呈现出二次性发育和丸体积与坦纳5期一致.
- 骨年龄显著提升,接近11岁儿童的年龄.
- 超声波证实丸体积大于年龄相应的规范.
- 大脑MRI揭示了垂体小腺瘤作为CPP的原因.
结论:
- 下垂体微腺瘤可以导致年轻男性中部早发性.
- 综合性临床评估与神经成像相结合,对于诊断CPP和确定其病因至关重要.
- 早期诊断和治疗CPP对于优化长期健康结果至关重要.
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