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Updated: Jan 14, 2026

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单细胞和空间转录组学揭示了自然杀手/T细胞淋巴瘤中瘤内部异质性和免疫逃避

Shuyun Ma1,2, Biaojie Huang3,4, Jiahui Wang1

  • 1Department of Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

iScience
|October 27, 2025
PubMed
概括

这项研究揭示了自然杀手/T细胞淋巴瘤 (NKTCL) 中明显的恶性细胞程序. 抑制脂肪酸结合蛋白5 (FABP5) 显示出治疗这种侵袭性癌症的前景.

关键词:
癌症 癌症 癌症 癌症微观环境是一个微观环境.文字转录学 (Transcriptomics) 是一个学科.

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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