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Updated: Jan 6, 2026

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors
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在急性髓性白血病中使用Venetoclax和新的BCL-2抑制剂

Pasquale Niscola1, Gianfranco Catalano2,3, Gloria Pasqualini3

  • 1Hematology Unit, S. Eugenio Hospital (ASL Roma 2), Rome, Italy.

Expert opinion on pharmacotherapy
|October 27, 2025
PubMed
概括

与venetoclax一样的B细胞淋巴瘤-2 (BCL-2) 抑制剂,通过诱导亡,正在彻底改变急性髓性白血病 (AML) 治疗. 研究正在探索新的组合和生物标志物,以克服耐药性并改善结果.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.BH3模仿的是 BH3 的模仿.低甲化剂是一种低甲化剂.强化化学疗法强化化疗法有针对性的治疗方法.维尼托克莱克斯 (Venetoclax) 是一个

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