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Updated: Jan 14, 2026

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在与年龄相关的嗅觉功能障碍中,嗅觉障碍-消极陈述问卷的有用性
Alexander Duffy1, Zachary M Soler1, Kristina A LaPointe1
1Department of Otolaryngology, Medical University of South Carolina, Charleston, SC, USA.
American journal of rhinology & allergy
|October 27, 2025
概括
嗅觉功能障碍 (OD) 在老年人中很常见. 嗅觉障碍-消极陈述问卷 (QOD-NS) 显示与测试的相关性很弱,可能不是老年人可靠的查工具.
科学领域:
- 老年学是一门学科.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 心理学 心理学 心理学
背景情况:
- 嗅觉功能障碍 (OD) 在老年成年人中被认可不足.
- 之前的研究表明,嗅觉障碍-消极陈述问卷 (QOD-NS) 可能在慢性鼻炎中选OD.
- 这项研究调查了QOD-NS在新型老龄化人口中的实用性.
研究的目的:
- 检查QOD-NS得分与老年成人心理物理嗅觉功能的相关性.
- 评估QOD-NS得分和嗅觉相关患者报告的结果指标 (PROM) 之间的关系.
- 评估QOD-NS作为在这个人口群体中潜在的OD查工具.
主要方法:
- 针对健康成年志愿者的前性队列研究.
- 参与者完成了QOD-NS,嗅觉相关的视觉模拟尺度 (VAS) 问题,嗅探棒 (TDI),De Jong Giervald孤独量表,UCLA孤独调查 (UCLA) 和患者健康问卷-9 (PHQ9).
- 统计分析包括相关性和接收器运行特征 (ROC) 曲线分析.
主要成果:
- 包括228名成年人 (平均年龄为50.3±17.7岁).
- 年龄较大的受试者 (≥50岁) 患低血 (58.3%) 和无血 (9.1%) 的患病率较高,QOD-NS和VAS得分较差 (P < 0.001).
- 在老年人中,QOD-NS与TDI (r = -0.386),VAS分数和PHQ9有显著的相关性,尽管相对较弱.
结论:
- 在老年人中,QOD-NS与心理物理测试和心理社会PROM有显著但较弱的相关性.
- 一个8.0的最佳QOD-NS截止值给出了0.23的Youden指数来检测dysosmia.
- 低的尤登指数表明QOD-NS作为老年患者嗅觉功能障碍的独立查工具的潜力有限.
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