SPI1/LILRB2轴通过与TLR8信号交叉声调节巨细胞耐受性:对败血症免疫疗法的影响

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DuJiang Yang1, Zhijun Ye1, Junjie Chen1

  • 1Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, NO.182, Chunhui Road, Longmatan District, Luzhou, 646000, Sichuan Province, People's Republic of China.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]
|October 27, 2025
PubMed
概括

研究人员发现,转录因子SPI1 (PU.1) 上调LILRB2,抑制免疫信号,促进巨细胞的耐受性. 这一途径为炎症状况提供了潜在的治疗点.

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