Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

282
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
282
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

4.1K
A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
4.1K
Improving Translational Accuracy02:07

Improving Translational Accuracy

14.1K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
14.1K
Improving Translational Accuracy02:07

Improving Translational Accuracy

3.5K
3.5K
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

1.1K
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
1.1K
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

9.0K
The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
9.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Does insulin bolster antioxidant defenses via the extracellular signal-regulated kinases-protein kinase B-nuclear factor erythroid 2 p45-related factor 2 pathway?

Antioxidants & redox signaling·2011
Same author

Decrease in calcium-sensing receptor in the progress of diabetic cardiomyopathy.

Diabetes research and clinical practice·2011
Same author

JAMIE: A software tool for jointly analyzing multiple ChIP-chip experiments.

Methods in molecular biology (Clifton, N.J.)·2011
Same author

Morphine-induced conditioned place preference in mice: metabolomic profiling of brain tissue to find "molecular switch" of drug abuse by gas chromatography/mass spectrometry.

Analytica chimica acta·2011
Same author

[The interventions effect-assessment of the workers exposed to N, N-dimethylformamide by percutaneous in a synthetic leather factory].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2011
Same author

[The analysis of effect of Th1/Th2 cytokine in the different prognosis in severe influenza A (H1N1)].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology·2011

相关实验视频

Updated: Jan 14, 2026

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.6K

PAVM:为稳健的注册提供渐进和自适应的变量最小化算法.

Hao Wu, Hongdi Liu, Tao Ding

    IEEE transactions on pattern analysis and machine intelligence
    |October 27, 2025
    PubMed
    概括
    此摘要是机器生成的。

    一个新的渐进和自适应差异最小化 (PAVM) 算法通过最小化结构偏差和异常点的扭曲来改善点云注册. 这种方法提高了复杂元件测量的精度.

    更多相关视频

    Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
    05:05

    Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

    Published on: November 23, 2019

    8.4K
    Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
    02:09

    Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

    Published on: April 12, 2024

    983

    相关实验视频

    Last Updated: Jan 14, 2026

    Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
    07:13

    Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

    Published on: October 27, 2023

    1.6K
    Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
    05:05

    Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

    Published on: November 23, 2019

    8.4K
    Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
    02:09

    Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

    Published on: April 12, 2024

    983

    科学领域:

    • 计算机视觉 计算机视觉
    • 几何计算几何计算
    • 计量学 计量学 计量学

    背景情况:

    • 强大的刚性点云注册对于精确测量复杂组件至关重要.
    • 现有的算法在与结构偏差,异常点和测量缺陷引起的匹配扭曲作斗争.
    • 目前的方法,如VMM和WPMAVM提供有限的改进,特别是许多异常点.

    研究的目的:

    • 引入一种新的算法,即渐进和自适应变量最小化 (PAVM),以克服刚性点云注册的局限性.
    • 增强对结构偏差和点云数据中的异常点的稳定性.
    • 提高复杂组件点云注册的速度,稳定性和通用性.

    主要方法:

    • 为全面的初始优化开发了一种渐进式的伪重量减轻策略.
    • 采用大约截止的重量函数来减少异常点的影响.
    • 引入了自适应协调距离功能,结合对称点对平面和点对点指标,以提高速度和稳定性.

    主要成果:

    • PAVM算法显示出强大的抗异常干扰能力和二次趋同.
    • 实验结果验证了与现有方法相比,在趋同稳定性,匹配速度和通用性方面取得的显著改进.
    • 该算法有效地处理各种复杂组件的注册任务.

    结论:

    • PAVM算法为刚性点云注册提供了一个强大的解决方案,有效地解决扭曲和异常点.
    • 其增强的速度,稳定性和通用性使其适用于各种工业和科学应用.
    • 通过使用点云数据,PAVM在精确定位和测量复杂物体方面取得了重大进展.