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快速分散的双酸盐片的开发和表征:压缩性研究和内PBPK建模

Uroosa Maqbool1, Farya Zafar1, Riffat Yasmin2

  • 1Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan.

PloS one
|October 27, 2025
PubMed
概括

这项研究通过直接压缩优化了快速溶解的二氨酸片,实现了出色的机械强度和快速释放药物. 体模型证实了可比的药理动力学参数,提供了具有成本效益和患者友好的剂型.

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