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作为多酶Aβ降解途径中的关键酶,内甲素转化酶1的表征

Irem Ulku1,2, Fatima El Ansari2, Mark A Hancock2

  • 1Integrated Program in Neuroscience, McGill University, Montreal, QC H3G 0B1, Canada.

Proceedings of the National Academy of Sciences of the United States of America
|October 27, 2025
PubMed
概括

内甲素转化酶1 (ECE1) 降解了阿尔茨海默病 (AD) 指标Aβ34,产生了一个新的生物标志物碎片. 这一发现为新的诊断工具提供了潜在的潜力,以检测粉样蛋白清除 in vivo.

关键词:
降解Aβ的酶可以降解Aβ.粉样蛋白清除率是什么末端蛋白转化酶 1 1 转化酶β-氨基化物是什么?

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