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双边风湿性视网膜脱落是由帕佐帕尼布诱导的,经过硬膜曲治疗
Eline Gelin De Raeymaecker1, Peter Stalmans
1Department of Ophthalmology, UZ Leuven, Leuven, Belgium.
Retinal cases & brief reports
|October 27, 2025
概括
在接受pazopanib.患者的双边风湿性视网膜脱落治疗中,膜曲有效地治疗了双边风湿性视网膜脱落. 这种方法可能比激光视网膜外科更好,用于管理这种罕见的帕佐帕尼布诱导的并发症.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
背景情况:
- 帕佐帕尼布是一种用于细胞癌的氨酸激酶抑制剂.
- 脊髓性视网膜脱落 (RRD) 是一种罕见但严重的眼部并发症,与巴佐帕尼布治疗有关.
- 这一案例凸显了识别向癌症治疗的眼部副作用的重要性.
研究的目的:
- 报告在巴佐帕尼布治疗后出现双边RRD的病例.
- 讨论选择缩骨而不是其他手术干预的理由.
- 为了解帕佐帕尼布诱导的眼睛毒性做出贡献.
主要方法:
- 一个病例报告是一名67岁的女性患者,患有转移性清晰细胞脏细胞癌,接受了pazopanib治疗.
- 患者患有双边RRD与黄斑参与.
- 膜曲是手术在两只眼睛进行的.
主要成果:
- 膜曲导致了双眼的立即和持续的视网膜重新连接.
- 患者在手术后经历了急性双侧外围膜炎症.
- 在术后也注意到左眼的慢性疼痛.
结论:
- 膜曲是一种有效的治疗巴佐帕尼布相关的RRD.
- 与激光视网膜切除术的帕斯普拉纳视网膜切除术相比,缩的缩可能是首选的手术选择.
- 需要进一步的研究来阐明巴佐帕尼布与术后炎症和疼痛综合征之间的联系.
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