具有系统性过敏的IgG4阳性结膜瘤:一个病例报告
Yuxuan Deng1, Lin Luo1, Zhanyu Zhou1
1Qingdao Municipal Hospital, Qingdao Hospital of University of Health and Rehabilitation Sciences, Qingdao, China.
Ocular immunology and inflammation
|October 27, 2025
概括
这份病例报告详细介绍了一位患有过敏性鼻炎和喘的患者罕见的IgG4相关的结膜瘤. 手术切除和治疗缓解了症状,突出了IgG4相关的眼部疾病.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
- 病理学 病理学 病理学
背景情况:
- 免疫球蛋白G4相关疾病 (IgG4-RD) 是一种影响各种器官的纤维炎症性疾病.
- 结膜干扰是罕见的,而这种情况呈现出一种独特的表现.
研究的目的:
- 报告一个IgG4阳性结膜瘤病例.
- 讨论其与过敏状况和IgG4相关疾病的关联.
主要方法:
- 一个55岁的女性病例报告,眼睛症状持续.
- 诊断工作包括体检,CT扫描,实验室测试 (IgG4水平) 和组织病理学分析.
- 进行了结膜瘤的外科切除.
主要成果:
- 患者出现双边眼睛和眼胀,最初被视为过敏结膜炎.
- 组织病理学证实结膜瘤的IgG4+血细胞/HPF>50和IgG4+/IgG+比率为~60%,诊断出IgG4相关的结膜瘤.
- 发现血清IgG4水平升高 (844 mg/dL).
结论:
- 孤立的过敏结膜炎可能是IgG4相关疾病的表现.
- 手术切除和皮质类固醇治疗可以缓解症状.
- 由于IgG4相关的眼部疾病可能涉及多器官的风险,长期跟踪至关重要.
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