地中海饮食治疗刺激性肠综合征:一项随机临床试验
Joy O Bamidele1, Grace M Brownlow1, Rosie M Flack1
1Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom (J.O.B., G.M.B., R.M.F., M.G.S.).
地中海饮食 (MD) 与传统的饮食建议 (TDA) 一样有效,用于控制易怒肠综合征 (IBS) 症状. 这项研究表明,MD对于IBS患者来说是一种可行的一线饮食选择.
科学领域:
- 胃肠病学 胃肠病学
- 饮食干预 饮食干预
- 临床试验 临床试验
背景情况:
- 刺激性肠综合征 (IBS) 管理往往缺乏基于证据的饮食指南.
- 推传统饮食建议 (TDA) 作为第一线,低FODMAP饮食作为第二线.
- 地中海饮食 (MD) 显示了IBS症状改善的潜力.
研究的目的:
- 为了评估地中海饮食 (MD) 是否与传统饮食建议 (TDA) 相比,在管理IBS症状方面没有劣势.
主要方法:
- 一个随机的非劣势性临床试验,涉及139名英国IBS患者.
- 参与者按照MD或TDA进行了6周的治疗.
- 主要结局:临床反应 (IBS-SSS减少≥50点);次要结局包括症状严重程度,心理健康和生活质量.
主要成果:
- 与TDA组 (42%) 相比,MD组显示出显著更高的临床响应率 (62%).
- 医学医学证明了对TDA的非劣势性和优势性,IBS症状严重程度等级 (IBS-SSS) 的得分下降更大.
- 在情绪,身体症状或生活质量方面没有观察到显著差异,但MD的坚持得到改善.
结论:
- 地中海饮食 (MD) 对IBS症状管理的传统饮食建议 (TDA) 不逊色,更优越.
- 对于患有IBS的人来说,MD是一种潜在的第一线饮食干预.
- 需要进一步的研究来评估长期影响.
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