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Updated: Jan 14, 2026

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice
10:28

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice

Published on: May 24, 2018

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超越单剂量人体质量平衡研究:尽量减少受试者限制,并通过一种新的多剂量设计建议,实现真正的稳定状态评估

Shuai Wang1, Weiping Zhao1, Sandhya Mandlekar2

  • 1Drug Metabolism and Pharmacokinetics, Genentech, Inc., 1 DNA Way, South San Francisco, California.

Drug metabolism and disposition: the biological fate of chemicals
|October 27, 2025
PubMed
概括

这项研究为人类质量平衡研究引入了一种新的多重剂量方法. 这种方法可以缩短受试者的限制时间,并改善药物代谢和稳定状态清除的评估.

关键词:
人类质量平衡研究研究多重剂量的多重剂量.一次剂量的单剂量.稳定状态稳定状态试验对象被关押在一个地方.

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