一项为期两年的随访研究,研究了年轻一代风险较高的延迟睡眠 - 觉醒阶段障碍的过程及其对白天功能的影响
Sayaka Tomishima1, Yoko Komada2, Kosuke Tanioka3
1Japan Somnology Center, Institute of Neuropsychiatry, Tokyo, Japan.
Sleep medicine
|October 27, 2025
概括
这项研究跟踪了年轻成年人的延迟睡眠-清醒阶段障碍 (DSWPD). 早期干预对于新的DSWPD病例至关重要,而改善的个体由于持续的睡眠问题需要持续监测.
科学领域:
- 时间生物学 时间生物学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 延迟睡眠-觉醒阶段障碍 (DSWPD) 影响年轻人群,影响日常功能.
- 在一般年轻人群中,关于风险性DSWPD的患病率和病程的纵向数据有限.
研究的目的:
- 在年轻的一般人群中调查风险较高的延迟睡眠-清醒阶段障碍 (DSWPD) 的纵向过程.
- 为了确定持续处于风险,新发作或从DSWPD中改善的个体的特征和结果.
主要方法:
- 一项为期两年的对2375名个人 (最初为7810人) 的随访调查评估了睡眠习惯,白天功能和DSWPD风险,使用BRIAN尺度和缺勤率.
- 患DSWPD的风险是由BRIAN分数≥40和每月≥4个缺席日定义的.
- 经过验证的问卷 (工作限制问卷,SF-8,K6) 测量了工作生产力,生活质量和心理困扰.
主要成果:
- 在随访时,1.9%的人面临DSWPD的风险. 在最初有风险的人中,14.5%的人仍然有风险 (占总数的0.5%).
- 持续有风险的个体表现出更高的缺勤率.
- 新发 DSWPD 与工作生产力和生活质量下降相关.
- 改善的个体减少了缺勤,但持续延迟了睡眠和清醒时间表,心理困扰得分更差.
结论:
- 建议对新诊断为DSWPD的个人进行早期干预.
- 对于那些经过DSWPD改善的人来说,需要仔细监测,因为残留症状和延迟睡眠模式仍然存在.
- 这些发现强调了DSWPD的慢性性质及其对功能的影响,即使在明显改善后.
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