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在患有血液学疾病的患者中,用于内动脉瘤的流量转移

Isabelle Pelcher¹, Cassidy Werner¹, Daniel G Lynch¹

¹Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Neurointervention

|October 27, 2025

概括

流量转移支架有效治疗内动脉瘤. 然而,状细胞病 (SCD) 的患者经历了并发症,这表明需要针对血液学疾病进行量身定制的治疗.

科学领域:

神经学神经学
心血管医学心血管医学
血液学血液学血液学

背景情况:

流量转移支架是对内动脉瘤 (IA) 的主要治疗方法.
流量转移 (FD) 取决于减少动脉瘤堵塞的血液流动和内皮质化.
血液学障碍 (HDs) 可以改变血液动态和支架相互作用,可能影响FD疗效.

研究的目的:

评估各种血液学疾病 (HDs) 的患者的结果,这些患者在内动脉瘤 (IAs) 进行流量转移 (FD).
确定FD在患有特定血液病症的患者中的潜在风险和益处.

主要方法:

对11名患有HD的患者进行了回顾性图表审查,这些患者使用FD治疗IA.
疾病被归类为凝血病或血红蛋白病 (例如状细胞病[SCD]).
使用O'Kelly-Marotta (OKM) 评分评估的临床和放射性结果.

主要成果:

11名29名IA患者接受治疗;17名动脉瘤接受了FD.
3名SCD患者中有2名经历了手术后中风.
7名患者实现了完整的动脉瘤闭塞 (8例经过治疗的动脉瘤),OKM得分的平均时间为16.8个月.

结论:

流量转移显示,在患有HD的患者中,IA堵塞的可能性很大.
由于观察到的并发症,人们对在状细胞病 (SCD) 患者中使用FD存在担忧.
对于患有HD患者的流量转移的治疗策略需要个性化.

关键词:

流量转移的转移流量转移的转移血液学疾病血液学疾病血球蛋白病变是一种血球蛋白病变.内动脉瘤是一个内动脉瘤.状细胞疾病是一种状细胞疾病.

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