Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Patterns of Fever01:26

Patterns of Fever

3.8K
Before understanding the types and patterns of fever, it is essential to know its phases.
3.8K
Disorders of Leukocytes01:27

Disorders of Leukocytes

1.8K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
1.8K
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

543
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
543
Increased Body Temperature01:25

Increased Body Temperature

6.4K
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
6.4K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.9K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.9K
Differentiation of Common Myeloid Progenitor Cells01:15

Differentiation of Common Myeloid Progenitor Cells

3.9K
Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
3.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

[Intravascular large B-cell lymphoma of the nasal turbinate presenting with hemophagocytic lymphohistiocytosis: a case report and literature review].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

[The influence of preoperative CT image characteristics on the outcome of thoracoscopic surgery for chronic tuberculous empyema].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2025
Same author

Effect and mechanism of recombinant human fibroblast growth factor 18 on osteoporosis in OVX mice.

Climacteric : the journal of the International Menopause Society·2024
Same author

[Value of (18)F-FDG PET-CT imaging to predict epidermal growth factor receptor mutations in patients with lung squamous cell carcinoma].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2021
Same author

[Clonal-related transformation from Waldenström macroglobulinemia to diffuse large B cell lymphoma during the treatment of ibrutinib: a case report and literature review].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2020
Same author

[Prognostic value of bone marrow (18)F-FDG uptake pattern of pretreatment PET-CT in extranodal NK/T cell lymphoma].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2020

相关实验视频

Updated: Jan 14, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.8K

[反复发烧,持续的细胞衰竭]

Y Miao1, J Zhang2, H Zhang3

  • 1Department of Hematology, Lymphoma Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China Department of Oncology, Department of Hematology, Affiliated Hospital of Nantong University, Nantong 226001, China.

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
|October 27, 2025
PubMed
概括

血管内大B细胞淋巴瘤 (IVLBCL) 是一种罕见的癌症. 这一案例突出了IVLBCL的诊断挑战和攻击性,强调了诊断和治疗中需要多学科合作的必要性.

更多相关视频

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
09:57

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Published on: March 5, 2018

30.4K
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
09:01

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

14.6K

相关实验视频

Last Updated: Jan 14, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.8K
Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
09:57

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Published on: March 5, 2018

30.4K
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
09:01

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

14.6K

科学领域:

  • 血液学 血液学 血液学
  • 在瘤学瘤学.
  • 罕见疾病 罕见疾病

背景情况:

  • 血管内大B细胞淋巴瘤 (IVLBCL) 是一种不常见的大B细胞淋巴瘤的亚型.
  • 患者经常出现非特异性症状,使早期诊断复杂化.

研究的目的:

  • 报告一个具有挑战性的IVLBCL病例最初被误诊.
  • 强调在诊断和管理IVLBCL时采用多学科方法的重要性.
  • 为临床实践提供有关IVLBCL诊断和治疗的见解.

主要方法:

  • 一个64岁的女性病例报告,有沃尔登斯特罗姆巨型球蛋白血病史.
  • 使用正子发射断层扫描/计算机断层扫描 (PET/CT) 和上腺活检进行诊断.
  • 治疗包括R-CHOP化疗,随后确定中枢神经系统 (CNS) 的参与.
  • 在上腺活检审查后,诊断被修改为IVLBCL.

主要成果:

  • 患者最初出现了复发性发烧和全细胞衰竭.
  • 在PET/CT检测出上腺扩大,导致初步诊断为扩散型大B细胞淋巴瘤,未另有说明.
  • 在初始化疗后发现了中枢神经系统透.
  • 最终的诊断被证实为IVLBCL,但尽管进行了积极的治疗,疾病仍在进展,导致患者死亡.

结论:

  • 由于IVLBCL的罕见性和非特异性呈现,它带来了重大诊断挑战.
  • 涉及成像,病理学和临床专业知识的多学科合作对于准确的IVLBCL诊断至关重要.
  • IVLBCL的攻击性需要迅速和适当的管理策略,尽管结果在许多情况下仍然很差.