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Updated: Jan 14, 2026

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Hsp70护送网络的机制和监管

Anne Wentink1, Rina Rosenzweig2, Harm Kampinga3

  • 1Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.

Nature reviews. Molecular cell biology
|October 28, 2025
PubMed
概括

70kDa热冲击蛋白 (Hsp70) 网络,由J域蛋白 (JDP) 和核酸交换因子 (NEF) 调节,精确地控制蛋白质命运. 这种复杂的调节引导蛋白质进入折叠或降解途径,影响细胞平衡和疾病.

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