患有腹腔疾病的患者的牙裂液和唾液中的炎症参数:比较分析
Arife Sabancı1, Ömer Alperen Kırmızıgül2, Nazmi Özgen3
1Department of Periodontology, Inonu University, Malatya, Turkey. dtcicekarife@hotmail.com.
Clinical oral investigations
|October 28, 2025
概括
与健康人相比,无质饮食的乳病患者在唾液和牙裂液中表现出类似的口腔炎症标志物. 这表明饮食管理后口腔炎症概况正常化.
科学领域:
- 口腔健康研究 口腔健康研究
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
背景情况:
- 乳病 (CD) 是一种免疫媒介的肠病,与慢性炎症和口腔健康问题有关.
- 了解CD患者口腔炎症标志物对于管理相关并发症至关重要.
研究的目的:
- 为了比较炎症标志物 (Ca),caspase-1和瘤亡因子-α (TNF-α) 在牙裂液 (GCF) 和唾液中的炎症标志物.
- 评估坚持无质饮食的腹腔炎症患者的口腔炎症概况,与健康对照对比.
主要方法:
- 60名参与者被分为乳病 (n=30) 和健康对照组 (n=30).
- 记载了牙周参数 (GI,PI,BOP,PD);用ELISA分析了唾液和GCF样本的Ca,caspase-1和TNF-α.
主要成果:
- 在胰腺疾病患者和健康对照人群 (p > 0.05) 之间,没有发现唾液或GCF水平的Ca,caspase-1和TNF-α的显著差异.
- 牙周测量也没有显示群体之间的显著差异.
结论:
- 无质饮食的乳病患者表现出与全身健康个体相似的口腔炎症概况.
- 饮食管理似乎使腹腔炎症患者的口腔炎症环境正常化.
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