出生大小改变了中年教育水平和男性和女性晚年身体功能之间的纵向关联
Vilborg Kolbrun Vilmundardottir1,2, Alfons Ramel3,4, Milan Chang3
1The Icelandic Gerontological Research Center, Reykjavik, Iceland. vkv2@hi.is.
BMC geriatrics
|October 28, 2025
概括
中年阶段的教育水平较低与以后生活中的身体功能较差有关,特别是对于出生时体重指数 (PI) 较低的个体. 这种关联在一定程度上可以解释为一生中身体活动减少.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 健康的社会经济决定因素
背景情况:
- 身体功能对于健康的衰老和晚年独立至关重要.
- 社会经济地位 (教育) 和生活方式 (体育活动) 是已知的对身体功能的影响.
- 出生大小是子宫内营养的指标,可能会在整个生命过程中与这些因素相互作用.
研究的目的:
- 检查25年来中年教育与晚年身体功能之间的纵向关联.
- 调查出生大小是否会改变中年教育和晚年身体功能之间的关系.
主要方法:
- 利用了来自1604名参与者的年龄基因/环境敏感性 (AGES) - 雷克雅未克研究的数据.
- 采用多变量线性回归,以步行速度 (GS) 和定时升级和启动 (TUG) 为结果.
- 根据出生时的体重指数 (PI) 进行分层分析,以评估效应的改变.
主要成果:
- 较低的教育程度 (小学与学院/大学) 与生命晚期更慢的GS和更长的TUG时间有关.
- 出生大小改变了这一关联;低PI的个体表现出明显更差的身体功能与较低的教育.
- 在高PI组中没有观察到教育和身体功能之间的显著关联.
结论:
- 教育水平较低与生命晚期身体功能较差有关,特别是在出生时小的孩子身上.
- 这种关联可能是由身体活动水平在整个生命过程中的差异介导的.
- 研究结果强调了生命周期视角对于理解健康衰老和潜在干预措施的重要性.
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