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Updated: Jan 13, 2026

Microtubule Plus-End Dynamics Visualization in Huntington's Disease Model based on Human Primary Skin Fibroblasts
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与HLD6相关的TUBB4A突变蛋白对细胞形态发生的影响

Yuki Kasamatsu1, Mei Tanaka1, Minori Minegishi1

  • 1Laboratory of Molecular Neurology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.

BMC research notes
|October 28, 2025
PubMed
概括

在TUBB4A中发生的突变会通过破坏寡质质细胞分化,导致6型低髓性白血病 (HLD6). 这导致细胞结构异常,中枢神经系统 (CNS) 的髓化受损.

关键词:
在髓化之前的分化.在 HLD6LD 中,微管是微管中的一个.基体细胞的基体细胞.管道4A 管道4A 管道

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