儿童缺铁性贫血和牙损伤之间的关联:系统的雨元分析
Mohammed Taib Fatih1, Mohammed Khalid Mahmood2, Yad Mariwan Mohammed Ali3
1Department of Dentistry, Komar University of Science and Technology, Sulaymaniyah, Iraq.
概括
患有缺铁性贫血 (IDA) 的儿童患牙损伤的可能性是牙损伤的三倍以上. 这一系统性审查强调了IDA与儿科患者牙损伤风险增加之间的显著关联.
科学领域:
- 儿科健康 儿科健康
- 营养缺乏症 营养缺乏症
- 口腔健康 口腔健康
背景情况:
- 牙腐烂和缺铁性贫血 (IDA) 是严重的公共卫生问题,特别是在儿童发育.
- 新出现的证据表明,IDA与牙损的流行之间存在潜在联系.
研究的目的:
- 系统地评估儿童和青少年缺铁性贫血和牙损伤之间的关联.
- 进行现有元分析的总体元分析,以综合当前的证据.
主要方法:
- 针对2025年1月之前发表的研究,对符合PRISMA的数据库 (PubMed,Scopus,Web of Science,Google Scholar) 进行了全面的搜索.
- 包括重点关注儿童和青少年 (<18岁) 的元分析. 统计措施包括几率比率 (OR) 和平均差异 (MD) 与95%置信区间 (CI).
- 使用I2和Cochran的Q测试评估异质性,使用Egger的测试评估出版偏差,使用AMSTAR 2评估研究质量,使用GRADE评估证据确定性.
主要成果:
- 五个元分析被纳入了审查.
- 患有IDA的儿童患有牙损伤的可能性超过三倍 (OR = 3.64,95% CI:2.45至5.40).
- 综合分析表明,脏儿童的血清费里和血红蛋白水平趋于降低,尽管在统计学上并不显著. 在患有虫的儿童中,MCV水平也呈现出较低值的非显著趋势.
结论:
- 与非贫血儿童相比,贫血儿童的牙损伤明显更为普遍.
- 关于IDA和牙腐烂之间的关联的证据的总体确定性很低,需要进一步调查.
相关概念视频
01:15Teeth
1.6K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.6K
01:21Tooth Anatomy
2.0K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.0K
01:31Essential Minerals for Bone Health
5.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
5.9K
01:26Minerals
1.1K
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Major...
Major...
1.1K
01:25Role of Vitamins in Maintaining Bone Health
5.0K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.0K
01:20Study Designs in Epidemiology
876
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
876