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在患有癌症和血液疾病的儿童中,神经认知功能障碍的共享社会人口统计风险因素
Claire E F Miller1, Jamie Neiman Luehring2, Elizabeth B Molina Kuna3
1Division of Pediatric Hematology, Oncology, and Bone Marrow Transplant, Department of Pediatrics, Primary Children's Hospital, University of Utah, Salt Lake City, Utah, USA.
Pediatric blood & cancer
|October 28, 2025
概括
较低的家庭收入与患有癌症和血液疾病的儿童神经认知功能较差有关. 这凸显了社会经济地位对认知发展的影响,以及对收入相关差异的进一步研究的需要.
科学领域:
- 儿科健康 儿科健康
- 神经科学是一个神经科学.
- 健康的社会决定因素
背景情况:
- 调查儿童神经认知功能中的健康社会决定因素 (SDoH).
- 专注于患有急性淋巴细胞白血病 (ALL),中枢神经系统 (CNS) 瘤和状细胞疾病 (SCD) 的儿童.
研究的目的:
- 检查SDoH与ALL,中枢神经系统瘤和SCD儿童的神经认知表现之间的关联.
- 确定影响认知结果的特定SDoH因素.
主要方法:
- 在这项研究中,有58个儿童照顾者二合一参与了这项研究.
- 社会经济地位 (SES) 组成部分,种族/种族,婚姻状况和邻里剥夺被评估为SDoH.
- 通过NIH工具箱认知电池 (NIHTB-CB) 流体认知子测试来评估神经认知功能.
主要成果:
- 家庭收入与工作记忆,处理速度和流体认知复合分数有显著的关联.
- 除了种族/种族之外,没有其他SDoH因素与诊断组的神经认知功能有显著的关联.
- 在控制诊断,年龄和性别后,家庭收入仍然是神经认知表现的重要预测因素.
结论:
- 较低的家庭收入是关键的社会经济因素,与接受癌症和血液疾病治疗的儿童神经认知功能下降有关.
- 需要进一步的研究来阐明家庭收入如何影响神经认知发展的机制.
- 研究结果表明,需要进行干预措施,以减轻低收入对儿科患者神经认知结果的影响.
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